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Conferences > BODA > 2015 > BT1A > BT1A.6

Identification & Quantification of Iron Deposits in Sickle Cell Disease Tissue by Label-Free Multi-Photon Microscopy

Genevieve D. Vigil, Alexander J. Adami, Biree Andemariam, Roger S. Thrall, and Scott S. Howard

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Abstract

Iron-complex deposits were identified in humanized sickle cell disease mouse splenic tissue by multi-photon microscopy (MPM) using intrinsic fluorescence. MPM emission spectra and morphological features were quantitatively compared to standard histological methods.

© 2015 Optical Society of America

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