Cytometry via Optical Wavefront Sensing

James Jacob; William Sullivan; John Hoffnagle

doi:10.1364/BODA.2011.BTuD5

Optics in the Life Sciences
OSA Technical Digest (CD) (Optica Publishing Group, 2011),
paper BTuD5
•https://doi.org/10.1364/BODA.2011.BTuD5

Cytometry via Optical Wavefront Sensing

James Jacob, William Sullivan, and John Hoffnagle

Bio-Optics: Design and Application 2011

Monterey, California United States
4–6 April 2011
ISBN: 978-1-55752-909-1

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BODA Postdeadline Session (BTuD)

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J. Jacob, W. Sullivan, and J. Hoffnagle, "Cytometry via Optical Wavefront Sensing," in Optics in the Life Sciences, OSA Technical Digest (CD) (Optica Publishing Group, 2011), paper BTuD5.

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Abstract

We describe a new technique to non-invasively analyze cells. A wavefront sensor measures the aberrations imparted onto a laser that illuminates single cells. The Zernike coefficients of the deformed wavefront comprise a unique cellular signature.

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