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Biophysical Model Estimation from Multispectral Intrinsic Optical Imaging in a Rat Model of Epilepsy

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Abstract

The hemodynamic responses to 4-AP induced focal epileptic spikes and electrical stimulations are compared in a rat model. Nonlinearities are quantified with biophysical models. Supranormal oxygen consumption from epileptic spikes is inferred.

© 2012 Optical Society of America

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