Quantifying Mitochondrial Dynamics in Apoptotic Cells with Optical Gabor-Like Filtering

Robert M. Pasternack; Jing-Yi Zheng; Nada N. Boustany

doi:10.1364/BIOMED.2010.BTuE3

Biomedical Optics and 3-D Imaging
OSA Technical Digest (CD) (Optica Publishing Group, 2010),
paper BTuE3
•https://doi.org/10.1364/BIOMED.2010.BTuE3

Quantifying Mitochondrial Dynamics in Apoptotic Cells with Optical Gabor-Like Filtering

Robert M. Pasternack, Jing-Yi Zheng, and Nada N. Boustany

Biomedical Optics 2010

Miami, Florida United States
11–14 April 2010
ISBN: 978-1-55752-887-2

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R. M. Pasternack, J. Zheng, and N. N. Boustany, "Quantifying Mitochondrial Dynamics in Apoptotic Cells with Optical Gabor-Like Filtering," in Biomedical Optics and 3-D Imaging, OSA Technical Digest (CD) (Optica Publishing Group, 2010), paper BTuE3.

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Abstract

We demonstrate a rapid throughput optical scatter method based on Gabor-like filtering to measure subcellular dynamics within single apoptotic cells. The technique is sensitive to a decrease in particle orientation consistent with apoptosis-induced mitochondrial fragmentation.

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