This goal of this study was to employ x-ray guided diffuse optical tomography to investigate the typical and quantitative optical findings that can be used to distinguish between osteoarthritis (OA) and psoriatic arthritis (PA) patients as well as healthy volunteers. Enhanced x-ray guided reconstruction results show that the optical properties between OA, PA and healthy joints are clearly different, suggesting that these functional imaging parameters could be used to diagnose OA or PA and monitor its progression.

© 2010 Optical Society of America

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