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Conferences > BIOMED > 2008 > BWB > BWB3

Multi-Modality Optical Imaging of Vascular Responses to Photodynamic Therapy in Mouse Window Chamber Model

Mamta Khurana, Hazel A. Collins, Eduardo H. Moriyama, Adrian Mariampillai, Harry L. Anderson, and Brian C. Wilson

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Abstract

We demonstrate multi-modal optical imaging in a window-chamber vascular model to investigate the response to photodynamic therapy using novel photosensitizers with high 2-γ cross-section, and show that (micro)vessel closure is feasible at clinically-realistic doses.

© 2008 Optical Society of America

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