Neural interferometry: first non-contact measurements of action potential-induced nerve swelling

Christopher Fang-Yen; Mark Chu; H. Sebastian Seung; Kamran Badizadegan; Ramachandra R. Dasari; Michael S. Feld

doi:10.1364/BIO.2004.WE6

Biomedical Topical Meeting
OSA Technical Digest (Optica Publishing Group, 2004),
paper WE6
•https://doi.org/10.1364/BIO.2004.WE6

Neural interferometry: first non-contact measurements of action potential-induced nerve swelling

Christopher Fang-Yen, Mark Chu, H. Sebastian Seung, Kamran Badizadegan, Ramachandra R. Dasari, and Michael S. Feld

Biomedical Topical Meeting 2004

Miami Beach, Florida United States
14–17 April 2004
ISBN: 1-55752-769-5

From the session
Biophysics and Physiology of Functional Neuroimaging (WE)

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C. Fang-Yen, M. Chu, H. S. Seung, K. Badizadegan, R. R. Dasari, and M. S. Feld, "Neural interferometry: first non-contact measurements of action potential-induced nerve swelling," in Biomedical Topical Meeting, OSA Technical Digest (Optica Publishing Group, 2004), paper WE6.

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Abstract

A novel heterodyne dual-beam interferometer is used to perform non-contact measurements of swelling displacements in a lobster nerve bundle during the action potential. Displacements are ~1-8 nm in amplitude and ~10 ms in duration.

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