Second harmonic generation for molecular contrast in optical coherence tomography

Brian E. Applegate; Changhuei Yang; Andrew M. Rollins; Joseph A. Izatt

doi:10.1364/BIO.2004.SB2

Biomedical Topical Meeting
OSA Technical Digest (Optica Publishing Group, 2004),
paper SB2
•https://doi.org/10.1364/BIO.2004.SB2

Second harmonic generation for molecular contrast in optical coherence tomography

Brian E. Applegate, Changhuei Yang, Andrew M. Rollins, and Joseph A. Izatt

Biomedical Topical Meeting 2004

Miami Beach, Florida United States
14–17 April 2004
ISBN: 1-55752-769-5

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Contrast Agents and Multiphoton Microscopy (SB)

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B. E. Applegate, C. Yang, A. M. Rollins, and J. A. Izatt, "Second harmonic generation for molecular contrast in optical coherence tomography," in Biomedical Topical Meeting, OSA Technical Digest (Optica Publishing Group, 2004), paper SB2.

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Abstract

We discuss the relative advantages of dark versus bright field approaches for achieving molecular contrast with OCT, and introduce second harmonic detection as a promising novel example of dark-field, coherence-gated microstructural imaging.

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