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Immuno - targeted gold nanoparticles as in - vivo molecular - specific contrast agents for optical detection of carcinogenesis

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Abstract

We present continuing developments of immuno - targeted gold nanoparticles as reflectance-based optical contrast agents for cancer-detection in - vivo. We demonstrate the ability to label EGFR (a hallmark for epithelial cancer) in several models of increasing biological relevance

© 2004 Optical Society of America

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