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Real time calibrated fluorescence imaging of tissue in vivo by using the combination of fluorescence and cross-polarized reflection

Jianan Y. Qu

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Abstract

We describe a calibrated fluorescence endoscopic technique that uses ratio image of autofluorescence to cross-polarized reflection for characterization of tissue pathology. We demonstrate that the system can differentiate early malignant lesions from normal tissues in vivo at different organ sites.

© 2002 Optical Society of America

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