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In-vivo quantification of optical contrast agents using a combined frequency-domain and steady state technique

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Abstract

We measure the in-vivo time-dilution curves of contrast agents in a rat tumor model using broadband near-infrared spectroscopy and Gadolinium enhanced MRI. Results indicate differences in kinetics that may be useful for tracking changes in vasculature as a function of tumor status.

© 2002 Optical Society of America

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