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Conferences > BIO > 2002 > PD > PD3

Fluorescence Potentiometrie Depth-Specific Imaging of Neural Systems

Jonathan A. Fisher, David Rector, John George, Robert F. Rogers, Diego Contreras, Brian M. Salzberg, Lief Finkei, and Aijun G. Yodh

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Abstract

We describe the development of depth-specific imaging devices for imaging neural activity in vivo using voltage-sensitive fluorescent dyes. Results from phantom fluorescent object tests show that gradient index (GRIN) lens devices demonstrate promise for imaging scattered light fluoresence signals from deep (up to 150 pm below the surface) cortical layers.

© 2002 Optical Society of America

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