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Herein a two-step Tikhonov regularization-based reconstruction algorithm in fluorescence molecular tomography (FMT) was proposed. The suboptimal and optimal parameter was obtained in two steps alternately. Experimental results suggested that such technique outperform the traditional L-curve criterion that estimating the optimal parameter when applying into the FMT reconstruction.
© 2009 OSA, IEEE Photonics Society, SPIE, COS, CIC
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