A scanning fiber-optic endomicroscope with enhanced signal collection efficiency was developed for intrinsic two-photon fluorescence imaging of epithelial tissue. Ex vivo two-photon autofluorescence imaging were demonstrated for the first time from both epithelium and stroma of various biological tissues with such a flexible fiber-optic endomicroscope.

© 2009 OSA, IEEE Photonics Society, SPIE, COS, CIC

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