Abstract

A dual-beam Optical Coherence Tomography system has been developed, using a bespoke dual optical fibre, to simultaneously image microfluidic channel structures and measure high velocity flows (presently 250μm/s) from a single optical access point.

© 2018 The Author(s)

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  1. N. Shembekar, C. Chaipan, R. Utharala, and C.A. Merten, “Droplet-based microfluidics in drug discovery, transcriptomics and high-throughput molecular genetics”, Lab Chip 16, 1314–1331 (2016).
    [Crossref]
  2. C. Cierpka and C.J. Kahler, “Particle imaging techniques for volumetric three-component (3D3C) velocity measurements in microfluidics", J Vis (Tokyo) 15, 1–31 (2012).
    [Crossref]
  3. R. Lima, S. Wada, K. Tsubota, and T. Yamaguchi, “Confocal micro-PIV measurements of three-dimensional profiles of cell suspension flow in a square microchannel”, Meas. Sci. Technol. 17, 797–808 (2006).
    [Crossref]
  4. R.A. Leitgeb, R.M. Werkmeister, C. Blatter, and L. Schmetterer, “Doppler Optical Coherence Tomography”, Prog Retin Eye Res. 41, 26–43 (2014)
    [Crossref]
  5. L.S. Magwaza, H.D. Ford, P.J.R. Cronje, U.L. Opara, S. Landahl, R.P. Tatam, and L.A. Terry, “Application of optical coherence tomography to non-destructively characterise rind breakdown disorder of ‘Nules Clementine’ mandarins”, Postharvest Biol. Technol. 84, 16–21 (2013).
    [Crossref]
  6. H.D. Ford and R.P. Tatam, “Passive OCT probe head for 3D duct inspection”, Meas. Sci. Technol., 24, 094001 (2013).
    [Crossref]
  7. S. Jonas, D. Bhattacharya, M.K. Khokha, and M.A. Choma, “Microfluidic characterization of cilia-driven fluid flow using optical coherence tomography-based particle tracking velocimetry”, Biomed. Opt. Express 2, 2022–2034 (2011).
    [Crossref]
  8. J.A. Izatt, M.A Choma, and A. Dhalla, “Theory of Optical Coherence Tomography” in Optical Coherence Tomography Technology and Applications 2nd edition W. Drexler and J.G. Fujimoto ed. (SpringerReference, Switzerland, 2015).
  9. J. Holmes, “Theory and applications of multi-beam OCT", Proc. SPIE 7139 (2008).
    [Crossref]
  10. D. Allan, T. Caswell, N. Keim, and C. van der Wel,, trackpy: Trackpy v0.3.2, 19th August 2016.
  11. J.C. Crocker and D.G. Grier, “Methods of Digital Video Microscopy for Colloidal Studies”, J. Colloid Interface Sci. 179, 298–310 (1996).
    [Crossref]

2016 (2)

N. Shembekar, C. Chaipan, R. Utharala, and C.A. Merten, “Droplet-based microfluidics in drug discovery, transcriptomics and high-throughput molecular genetics”, Lab Chip 16, 1314–1331 (2016).
[Crossref]

D. Allan, T. Caswell, N. Keim, and C. van der Wel,, trackpy: Trackpy v0.3.2, 19th August 2016.

2014 (1)

R.A. Leitgeb, R.M. Werkmeister, C. Blatter, and L. Schmetterer, “Doppler Optical Coherence Tomography”, Prog Retin Eye Res. 41, 26–43 (2014)
[Crossref]

2013 (2)

L.S. Magwaza, H.D. Ford, P.J.R. Cronje, U.L. Opara, S. Landahl, R.P. Tatam, and L.A. Terry, “Application of optical coherence tomography to non-destructively characterise rind breakdown disorder of ‘Nules Clementine’ mandarins”, Postharvest Biol. Technol. 84, 16–21 (2013).
[Crossref]

H.D. Ford and R.P. Tatam, “Passive OCT probe head for 3D duct inspection”, Meas. Sci. Technol., 24, 094001 (2013).
[Crossref]

2012 (1)

C. Cierpka and C.J. Kahler, “Particle imaging techniques for volumetric three-component (3D3C) velocity measurements in microfluidics", J Vis (Tokyo) 15, 1–31 (2012).
[Crossref]

2011 (1)

2008 (1)

J. Holmes, “Theory and applications of multi-beam OCT", Proc. SPIE 7139 (2008).
[Crossref]

2006 (1)

R. Lima, S. Wada, K. Tsubota, and T. Yamaguchi, “Confocal micro-PIV measurements of three-dimensional profiles of cell suspension flow in a square microchannel”, Meas. Sci. Technol. 17, 797–808 (2006).
[Crossref]

1996 (1)

J.C. Crocker and D.G. Grier, “Methods of Digital Video Microscopy for Colloidal Studies”, J. Colloid Interface Sci. 179, 298–310 (1996).
[Crossref]

Allan, D.

D. Allan, T. Caswell, N. Keim, and C. van der Wel,, trackpy: Trackpy v0.3.2, 19th August 2016.

Bhattacharya, D.

Blatter, C.

R.A. Leitgeb, R.M. Werkmeister, C. Blatter, and L. Schmetterer, “Doppler Optical Coherence Tomography”, Prog Retin Eye Res. 41, 26–43 (2014)
[Crossref]

Caswell, T.

D. Allan, T. Caswell, N. Keim, and C. van der Wel,, trackpy: Trackpy v0.3.2, 19th August 2016.

Chaipan, C.

N. Shembekar, C. Chaipan, R. Utharala, and C.A. Merten, “Droplet-based microfluidics in drug discovery, transcriptomics and high-throughput molecular genetics”, Lab Chip 16, 1314–1331 (2016).
[Crossref]

Choma, M.A

J.A. Izatt, M.A Choma, and A. Dhalla, “Theory of Optical Coherence Tomography” in Optical Coherence Tomography Technology and Applications 2nd edition W. Drexler and J.G. Fujimoto ed. (SpringerReference, Switzerland, 2015).

Choma, M.A.

Cierpka, C.

C. Cierpka and C.J. Kahler, “Particle imaging techniques for volumetric three-component (3D3C) velocity measurements in microfluidics", J Vis (Tokyo) 15, 1–31 (2012).
[Crossref]

Crocker, J.C.

J.C. Crocker and D.G. Grier, “Methods of Digital Video Microscopy for Colloidal Studies”, J. Colloid Interface Sci. 179, 298–310 (1996).
[Crossref]

Cronje, P.J.R.

L.S. Magwaza, H.D. Ford, P.J.R. Cronje, U.L. Opara, S. Landahl, R.P. Tatam, and L.A. Terry, “Application of optical coherence tomography to non-destructively characterise rind breakdown disorder of ‘Nules Clementine’ mandarins”, Postharvest Biol. Technol. 84, 16–21 (2013).
[Crossref]

Dhalla, A.

J.A. Izatt, M.A Choma, and A. Dhalla, “Theory of Optical Coherence Tomography” in Optical Coherence Tomography Technology and Applications 2nd edition W. Drexler and J.G. Fujimoto ed. (SpringerReference, Switzerland, 2015).

Ford, H.D.

H.D. Ford and R.P. Tatam, “Passive OCT probe head for 3D duct inspection”, Meas. Sci. Technol., 24, 094001 (2013).
[Crossref]

L.S. Magwaza, H.D. Ford, P.J.R. Cronje, U.L. Opara, S. Landahl, R.P. Tatam, and L.A. Terry, “Application of optical coherence tomography to non-destructively characterise rind breakdown disorder of ‘Nules Clementine’ mandarins”, Postharvest Biol. Technol. 84, 16–21 (2013).
[Crossref]

Grier, D.G.

J.C. Crocker and D.G. Grier, “Methods of Digital Video Microscopy for Colloidal Studies”, J. Colloid Interface Sci. 179, 298–310 (1996).
[Crossref]

Holmes, J.

J. Holmes, “Theory and applications of multi-beam OCT", Proc. SPIE 7139 (2008).
[Crossref]

Izatt, J.A.

J.A. Izatt, M.A Choma, and A. Dhalla, “Theory of Optical Coherence Tomography” in Optical Coherence Tomography Technology and Applications 2nd edition W. Drexler and J.G. Fujimoto ed. (SpringerReference, Switzerland, 2015).

Jonas, S.

Kahler, C.J.

C. Cierpka and C.J. Kahler, “Particle imaging techniques for volumetric three-component (3D3C) velocity measurements in microfluidics", J Vis (Tokyo) 15, 1–31 (2012).
[Crossref]

Keim, N.

D. Allan, T. Caswell, N. Keim, and C. van der Wel,, trackpy: Trackpy v0.3.2, 19th August 2016.

Khokha, M.K.

Landahl, S.

L.S. Magwaza, H.D. Ford, P.J.R. Cronje, U.L. Opara, S. Landahl, R.P. Tatam, and L.A. Terry, “Application of optical coherence tomography to non-destructively characterise rind breakdown disorder of ‘Nules Clementine’ mandarins”, Postharvest Biol. Technol. 84, 16–21 (2013).
[Crossref]

Leitgeb, R.A.

R.A. Leitgeb, R.M. Werkmeister, C. Blatter, and L. Schmetterer, “Doppler Optical Coherence Tomography”, Prog Retin Eye Res. 41, 26–43 (2014)
[Crossref]

Lima, R.

R. Lima, S. Wada, K. Tsubota, and T. Yamaguchi, “Confocal micro-PIV measurements of three-dimensional profiles of cell suspension flow in a square microchannel”, Meas. Sci. Technol. 17, 797–808 (2006).
[Crossref]

Magwaza, L.S.

L.S. Magwaza, H.D. Ford, P.J.R. Cronje, U.L. Opara, S. Landahl, R.P. Tatam, and L.A. Terry, “Application of optical coherence tomography to non-destructively characterise rind breakdown disorder of ‘Nules Clementine’ mandarins”, Postharvest Biol. Technol. 84, 16–21 (2013).
[Crossref]

Merten, C.A.

N. Shembekar, C. Chaipan, R. Utharala, and C.A. Merten, “Droplet-based microfluidics in drug discovery, transcriptomics and high-throughput molecular genetics”, Lab Chip 16, 1314–1331 (2016).
[Crossref]

Opara, U.L.

L.S. Magwaza, H.D. Ford, P.J.R. Cronje, U.L. Opara, S. Landahl, R.P. Tatam, and L.A. Terry, “Application of optical coherence tomography to non-destructively characterise rind breakdown disorder of ‘Nules Clementine’ mandarins”, Postharvest Biol. Technol. 84, 16–21 (2013).
[Crossref]

Schmetterer, L.

R.A. Leitgeb, R.M. Werkmeister, C. Blatter, and L. Schmetterer, “Doppler Optical Coherence Tomography”, Prog Retin Eye Res. 41, 26–43 (2014)
[Crossref]

Shembekar, N.

N. Shembekar, C. Chaipan, R. Utharala, and C.A. Merten, “Droplet-based microfluidics in drug discovery, transcriptomics and high-throughput molecular genetics”, Lab Chip 16, 1314–1331 (2016).
[Crossref]

Tatam, R.P.

L.S. Magwaza, H.D. Ford, P.J.R. Cronje, U.L. Opara, S. Landahl, R.P. Tatam, and L.A. Terry, “Application of optical coherence tomography to non-destructively characterise rind breakdown disorder of ‘Nules Clementine’ mandarins”, Postharvest Biol. Technol. 84, 16–21 (2013).
[Crossref]

H.D. Ford and R.P. Tatam, “Passive OCT probe head for 3D duct inspection”, Meas. Sci. Technol., 24, 094001 (2013).
[Crossref]

Terry, L.A.

L.S. Magwaza, H.D. Ford, P.J.R. Cronje, U.L. Opara, S. Landahl, R.P. Tatam, and L.A. Terry, “Application of optical coherence tomography to non-destructively characterise rind breakdown disorder of ‘Nules Clementine’ mandarins”, Postharvest Biol. Technol. 84, 16–21 (2013).
[Crossref]

Tsubota, K.

R. Lima, S. Wada, K. Tsubota, and T. Yamaguchi, “Confocal micro-PIV measurements of three-dimensional profiles of cell suspension flow in a square microchannel”, Meas. Sci. Technol. 17, 797–808 (2006).
[Crossref]

Utharala, R.

N. Shembekar, C. Chaipan, R. Utharala, and C.A. Merten, “Droplet-based microfluidics in drug discovery, transcriptomics and high-throughput molecular genetics”, Lab Chip 16, 1314–1331 (2016).
[Crossref]

van der Wel, C.

D. Allan, T. Caswell, N. Keim, and C. van der Wel,, trackpy: Trackpy v0.3.2, 19th August 2016.

Wada, S.

R. Lima, S. Wada, K. Tsubota, and T. Yamaguchi, “Confocal micro-PIV measurements of three-dimensional profiles of cell suspension flow in a square microchannel”, Meas. Sci. Technol. 17, 797–808 (2006).
[Crossref]

Werkmeister, R.M.

R.A. Leitgeb, R.M. Werkmeister, C. Blatter, and L. Schmetterer, “Doppler Optical Coherence Tomography”, Prog Retin Eye Res. 41, 26–43 (2014)
[Crossref]

Yamaguchi, T.

R. Lima, S. Wada, K. Tsubota, and T. Yamaguchi, “Confocal micro-PIV measurements of three-dimensional profiles of cell suspension flow in a square microchannel”, Meas. Sci. Technol. 17, 797–808 (2006).
[Crossref]

Biomed. Opt. Express (1)

J Vis (Tokyo) (1)

C. Cierpka and C.J. Kahler, “Particle imaging techniques for volumetric three-component (3D3C) velocity measurements in microfluidics", J Vis (Tokyo) 15, 1–31 (2012).
[Crossref]

J. Colloid Interface Sci. (1)

J.C. Crocker and D.G. Grier, “Methods of Digital Video Microscopy for Colloidal Studies”, J. Colloid Interface Sci. 179, 298–310 (1996).
[Crossref]

Lab Chip (1)

N. Shembekar, C. Chaipan, R. Utharala, and C.A. Merten, “Droplet-based microfluidics in drug discovery, transcriptomics and high-throughput molecular genetics”, Lab Chip 16, 1314–1331 (2016).
[Crossref]

Meas. Sci. Technol. (2)

R. Lima, S. Wada, K. Tsubota, and T. Yamaguchi, “Confocal micro-PIV measurements of three-dimensional profiles of cell suspension flow in a square microchannel”, Meas. Sci. Technol. 17, 797–808 (2006).
[Crossref]

H.D. Ford and R.P. Tatam, “Passive OCT probe head for 3D duct inspection”, Meas. Sci. Technol., 24, 094001 (2013).
[Crossref]

Postharvest Biol. Technol. (1)

L.S. Magwaza, H.D. Ford, P.J.R. Cronje, U.L. Opara, S. Landahl, R.P. Tatam, and L.A. Terry, “Application of optical coherence tomography to non-destructively characterise rind breakdown disorder of ‘Nules Clementine’ mandarins”, Postharvest Biol. Technol. 84, 16–21 (2013).
[Crossref]

Proc. SPIE (1)

J. Holmes, “Theory and applications of multi-beam OCT", Proc. SPIE 7139 (2008).
[Crossref]

Prog Retin Eye Res. (1)

R.A. Leitgeb, R.M. Werkmeister, C. Blatter, and L. Schmetterer, “Doppler Optical Coherence Tomography”, Prog Retin Eye Res. 41, 26–43 (2014)
[Crossref]

Trackpy v0.3.2 (1)

D. Allan, T. Caswell, N. Keim, and C. van der Wel,, trackpy: Trackpy v0.3.2, 19th August 2016.

Other (1)

J.A. Izatt, M.A Choma, and A. Dhalla, “Theory of Optical Coherence Tomography” in Optical Coherence Tomography Technology and Applications 2nd edition W. Drexler and J.G. Fujimoto ed. (SpringerReference, Switzerland, 2015).