Abstract
Fiber-optic endomicroscopy is a minimally invasive tool to probe disease progression with subcellular resolution. In this Letter, we demonstrate a low-cost and compact fluorescence microendoscope capable of line-scanning confocal imaging by synchronizing a digital light projector with a CMOS camera. We present the digital aperture design to enable real-time confocal imaging, and we implement parallel illumination to improve the optical sectioning performance. Furthermore, we show that the confocal microendoscope can enhance visualization of disease-associated features when imaging highly scattering esophageal specimens.
© 2019 Optical Society of America
Full Article | PDF ArticleMore Like This
Yubo Tang, Alex Kortum, Imran Vohra, Jennifer Carns, Sharmila Anandasabapathy, and Rebecca Richards-Kortum
Opt. Lett. 44(18) 4519-4522 (2019)
Yubo Tang, Alex Kortum, Sonia G. Parra, Imran Vohra, Andrea Milbourne, Preetha Ramalingam, Paul A. Toscano, Kathleen M. Schmeler, and Rebecca R. Richards-Kortum
Biomed. Opt. Express 11(1) 269-280 (2020)
Christian M. Jennings, Jason B. King, and Sapun H. Parekh
Opt. Lett. 47(16) 4191-4194 (2022)