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Calibration-free quantitative phase imaging in multi-core fiber endoscopes using end-to-end deep learning

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Abstract

Quantitative phase imaging (QPI) through multi-core fibers (MCFs) has been an emerging in vivo label-free endoscopic imaging modality with minimal invasiveness. However, the computational demands of conventional iterative phase retrieval algorithms have limited their real-time imaging potential. We demonstrate a learning-based MCF phase imaging method that significantly reduced the phase reconstruction time to 5.5 ms, enabling video-rate imaging at 181 fps. Moreover, we introduce an innovative optical system that automatically generated the first, to the best of our knowledge, open-source dataset tailored for MCF phase imaging, comprising 50,176 paired speckles and phase images. Our trained deep neural network (DNN) demonstrates a robust phase reconstruction performance in experiments with a mean fidelity of up to 99.8%. Such an efficient fiber phase imaging approach can broaden the applications of QPI in hard-to-reach areas.

© 2024 Optica Publishing Group

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Supplementary Material (2)

NameDescription
Dataset 1       Training dataset for quantitative phase imaging through a multi-core fiber bundle.
Dataset 2       Training dataset for quantitative phase imaging through a multi-core fiber bundle.

Data availability

The experimentally generated training datasets are available in Dataset 1, Ref. [21] and Dataset 2, Ref. [22].

21. J. Sun, “Training dataset 1 for reconstruct the phase image through a multi-core fiber bundle,” figshare (2023) https://doi.org/10.6084/m9.figshare.24932583.

22. J. Sun, “Training dataset 2 for reconstruct the phase image through a multi-core fiber bundle,” figshare (2023) https://doi.org/10.6084/m9.figshare.24932604.

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