Abstract
In this Letter, we propose, to the best of our knowledge, the first in-fiber optofluidic Raman surface-enhanced Raman spectroscopy (SERS) sensor based on a microstructured hollow fiber (MHF) with a suspended core. Taking advantage of the unique internal structure, we immobilize silver nanoparticles with an SERS effect in the MHF by chemical bonding. The Raman signal of the microfluidic sample is excited by the excitation light in the suspended core through an evanescent field. Then the online SERS signal can be coupled back into the core and detected. To demonstrate the feasibility of the device, rhodamine 6G is chosen as the analyte, and high-quality SERS spectra are detected with the limit of detection of . Furthermore, an online optofluidic test is conducted on ceftriaxone () to examine its capabilities in antibiotic sensing. The results show that the LOD of the samples is . Significantly, this Letter provides an integrated optofluidic in-fiber SERS sensor with a microchannel that can be integrated with chip devices without spatial optical coupling, which has a broad application in medicine and food safety, as well as various aspects of biological in-fiber sensing.
© 2019 Optical Society of America
Full Article | PDF ArticleMore Like This
Pingping Teng, Danheng Gao, Xinghua Yang, Meng Luo, Depeng Kong, Shuai Gao, Zhihai Liu, Zhanao Li, Xingyue Wen, Libo Yuan, Kang Li, Mark Bowkett, and Nigel Copner
Appl. Opt. 60(22) 6659-6664 (2021)
Xian Zhang, Xiao-Song Zhu, and Yi-Wei Shi
Opt. Lett. 44(18) 4550-4553 (2019)
Danheng Gao, Xinghua Yang, Pingping Teng, Meng Luo, Haoxin Zhang, Zhihai Liu, Jun Yang, Zhanao Li, Xingyue Wen, Libo Yuan, Kang Li, Mark Bowkett, and Nigel Copner
Opt. Lett. 46(5) 1101-1104 (2021)