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How the melanin concentration in the skin affects the fluorescence-spectroscopy signal formation

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Abstract

The influence of various melanin concentrations on the endogenous fluorescence intensity of biological tissue has been experimentally studied, and the fluorescence signals have been modeled by the Monte Carlo method. The modeling is based on a four-layer optical model of the skin, using known optical parameters of skin with various melanin concentrations. The fluorescence spectra obtained by the Monte Carlo method agrees with the results of the experimental investigations.

© 2016 Optical Society of America

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