Abstract
Raman spectroscopy is a powerful tool for studying the biochemical composition
of tissues and cells in the human body. We describe the initial results of a
feasibility study to design and build a miniature, fiber optic probe incorporated
into a standard hypodermic needle. This probe is intended for use in optical
biopsies of solid tissues to provide valuable information of disease type, such as
in the lymphatic system, breast, or prostate, or of such tissue types as muscle,
fat, or spinal, when identifying a critical injection site. The optical design and
fabrication of this probe is described, and example spectra of various ex vivo
samples are shown.
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