Abstract
Anisotropic structures such as myofibrils, collagen, and elastic fibers are prevalent in tissues. The orientations of these anisotropic structures are important indicators in various biomedical studies. Here we analyze the ability of using Mueller matrix polar decomposition (MMPD) and Mueller matrix transformation (MMT) parameters to determine and distinguish the accurate orientations of different anisotropies originated from scattering and birefringence in backscattering measurements. The experimental results of complex phantoms and Monte Carlo simulations suggest that the MMT and MMPD parameters can be used to reveal the orientations of the cylindrical scatterers and birefringence in turbid media, respectively. Moreover, a preliminary application of these Mueller matrix-derived parameters on bovine tendon samples demonstrates the ability of using the parameters to distinguish anisotropic scattering and birefringence orientations of tissues. The anisotropy orientation information can be helpful for biomedical studies or diagnosis.
© 2018 Optical Society of America
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