Abstract
An integrated endoscopy system for simultaneous imaging and spectroscopy was developed to facilitate more accurate and convenient detection of early lung cancers. A specially designed three-CCD camera in combination with a dedicated light source permits capture of both white-light color images and tissue autofluorescence images without the need to switch between two different cameras. A mirror with an optical fiber at its center, placed at an interim imaging plane inside the camera unit, facilitates simultaneous imaging and spectroscopy measurements in either white-light reflectance mode or fluorescence mode. The system has been successfully tested in a clinic, demonstrating a practical approach to improve both diagnostic sensitivity and specificity at the same time.
© 2004 Optical Society of America
Full Article | PDF ArticleMore Like This
A. N. Yaroslavsky, V. Neel, and R. R. Anderson
Opt. Lett. 29(17) 2010-2012 (2004)
Chung-Chieh Yu, Condon Lau, Geoff O’Donoghue, Jelena Mirkovic, Sasha McGee, Luis Galindo, Alphi Elackattu, Elizabeth Stier, Gregory Grillone, Kamran Badizadegan, Ramachandra R. Dasari, and Michael S. Feld
Opt. Express 16(20) 16227-16239 (2008)
Zhiwei Huang, Seng Khoon Teh, Wei Zheng, Jianhua Mo, Kan Lin, Xiaozhuo Shao, Khek Yu Ho, Ming Teh, and Khay Guan Yeoh
Opt. Lett. 34(6) 758-760 (2009)