Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Individual variations in the spatial profile of human macular pigment

Not Accessible

Your library or personal account may give you access

Abstract

Individual variations in the spatial profile of macular pigment (MP) density were measured for 32 subjects. Peak density of MP measured with a 460-nm, 12-arcmin stimulus averaged 0.58, standard deviation (SD) =0.26, with a range of 0.175 to 1.39. To assess the symmetry of the MP distribution, MP density was measured on the horizontal and vertical meridians at ±1 deg eccentricity. The density varied by no more than 16% at these four locations, indicating a basically symmetric distribution. Based on a linear interpolation between measured locations, the width of the spatial distribution of MP at half the maximal density averaged 1.03 deg, SD=0.38, with a range of 0.25 to 1.9 deg. The average spatial profile of MP density across subjects was fitted with both an exponential and a Gaussian function. An exponential decay with eccentricity explained more variance in the data than did a Gaussian function. Assuming an exponential decay with eccentricity, once MP density has been measured in the center of the retina (denoted A), MP density at more eccentric locations (X, deg) can be predicted with a standardized equation (MP=A×10-0.42x). For individual cases, small deviations from an exponential function suggest the existence of minor flanking peaks or shoulders for 40% of the subjects. We also examined the temporal stability of the MP profile of four subjects over a time span of 4–14 months and for a single spatial location for ten subjects over a time span of 1–16 years. These longitudinal data show that differences in MP density among subjects are maintained over time, if dietary patterns are stable.

© 1997 Optical Society of America

Full Article  |  PDF Article
More Like This
Bimodal spatial distribution of macular pigment: evidence of a gender relationship

François C. Delori, Douglas G. Goger, Claudia Keilhauer, Paola Salvetti, and Giovanni Staurenghi
J. Opt. Soc. Am. A 23(3) 521-538 (2006)

Nonmydriatic fluorescence-based quantitative imaging of human macular pigment distributions

Mohsen Sharifzadeh, Paul S. Bernstein, and Werner Gellermann
J. Opt. Soc. Am. A 23(10) 2373-2387 (2006)

Changes in spatial extent and peak double optical density of human macular pigment with age

António M. G. Baptista and Sérgio M. C. Nascimento
J. Opt. Soc. Am. A 31(4) A87-A92 (2014)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (8)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Tables (2)

You do not have subscription access to this journal. Article tables are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Equations (1)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved