Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Spectral dependence of temporal point spread functions in human tissues

Not Accessible

Your library or personal account may give you access

Abstract

We have determined the spectral dependence of the temporal point spread functions of human tissues experimentally between 740 and 840 nm in transmittance measurements on the adult head, forearm, and calf (in υivo) and the infant head (post mortem) by using picosecond laser pulses and a streak camera detector. Two parameters are extracted from the temporal point spread function; the differential path-length factor (DPF), calculated from the mean time, and the slope of the logarithmic intensity decay. In all tissues the DPF and the logarithmic slope show a reciprocal relationship and exhibit characteristics of the absorption spectra of hemoglobin. The DPF falls with increasing wavelength, the variation being typically 12%, while the logarithmic slope increases with wavelength. A quantitative analysis of the logarithmic slope spectrum significantly underestimated expected tissue chromophore concentrations. The absolute magnitudes of the DPF showed considerable intersubject variation, but the variation with wavelength was consistent and thus may be used in the correction of tissue attenuation spectra.

© 1993 Optical Society of America

Full Article  |  PDF Article
More Like This
Time-resolved diffuse optical tomographic imaging for the provision of both anatomical and functional information about biological tissue

Huijuan Zhao, Feng Gao, Yukari Tanikawa, Kazuhiro Homma, and Yukio Yamada
Appl. Opt. 44(10) 1905-1916 (2005)

Tissue oximetry: a comparison of mean values of regional tissue saturation, reproducibility and dynamic range of four NIRS-instruments on the human forearm

Simon Hyttel-Sorensen, Line C. Sorensen, Joan Riera, and Gorm Greisen
Biomed. Opt. Express 2(11) 3047-3057 (2011)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (9)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Equations (4)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved